Modified loadUserProfile function i discovered using mailuser interface from horfic after many tests and debugs functions recive a value iguals to userid field not sys_userid.
I keep sysuser_id testing for compatibility issues no have any idea if this used in another place and added aditional userid test. 
Tested all things and used auto-response with roundcube with this modifications all worked fine.
More info see here: http://www.howtoforge.com/forums/showthread.php?t=38437&page=15